ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 55 kDa in size corresponding to ZIC2 by western blotting in the appropriate cell lysate or extract.
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0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
HPE5, cb851, fb26a03, wu:fb26a03, zic2, zic2.1, Ku, Zic family member 2, zic family member 2 (odd-paired homolog, Drosophila), a, zinc finger protein of the cerebellum 2, ZIC2, Zic2, zic2a
ZIC2 (also known as zinc finger protein of the cerebellum 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog) is a nuclear protein that functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain. Synonyms: ZIC2, zinc finger protein of the cerebellum 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog