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SPRY4 Antikörper (Sprouty RTK Signaling Antagonist 4) AA 306-322 Primary Antibody

SPRY4 Reaktivität: Human IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN129626
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle SPRY4 Antikörper anzeigen
    SPRY4
    Bindungsspezifität
    • 11
    • 10
    • 8
    • 8
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 306-322
    Reaktivität
    • 64
    • 13
    • 11
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 64
    Kaninchen
    Klonalität
    • 64
    Polyklonal
    Konjugat
    • 22
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPRY4 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 43
    • 20
    • 15
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Schimpanse
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 306-322 of Human Sprouty-4 protein.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band (maybe a doublet) ~35 kDa in size corresponding to Sprouty-4 by western blotting in the appropriate cell lysate or extract.  Some non-specific banding may be observed using this antibody.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.1 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    SPRY4
    Andere Bezeichnung
    Sprouty-4 (SPRY4 Produkte)
    Synonyme
    SPRY4, LOC100218545, HH17, A030006O18Rik, sprouty4, sprouty RTK signaling antagonist 4, sprouty (Drosophila) homolog 4, sprouty homolog 4 (Drosophila), Spry4, SPRY4, spry4
    Hintergrund
    Sprouty-4 (also known as SPRY4) is an inhibitor of the insulin receptor and EGFR-transduced mitogen-activated protein kinase (MAPK) signaling pathway downstream of FGF and EGF receptor tyrosine kinase activation. It is positioned upstream of RAS activation and impairs the formation of active GTP-RAS.  SPRY4 is widely expressed, with different isoforms. The protein consists of 322 amino acids, with a cysteine-rich region, Src homology 3 binding regions, proline-rich regions, and a PEST sequence. It is expressed predominantly in the cytoplasm. Northern results show bands across most tissues, with strongest expression in heart, brain, placenta, lung, and intestine.
    Synonyms: Sprouty-4, SPRY4
    Gen-ID
    81848, 42741659
    UniProt
    P08183
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