SPRY4 Antikörper (Middle Region)

Produktnummer ABIN2784290

Produktdetails anti-SPRY4 Antikörper

Target: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPRY4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LCYLPATGCV KLAQRGYDRL RRPGCRCKHT NSVICKAASG DAKTSRPDKP

Homologie: Cow: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SPRY4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPRY4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 322 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SPRY4

Target: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Andere Bezeichnung: SPRY4 (SPRY4 Produkte)

Synonyme: SPRY4 antikoerper, LOC100218545 antikoerper, HH17 antikoerper, A030006O18Rik antikoerper, sprouty4 antikoerper, sprouty RTK signaling antagonist 4 antikoerper, sprouty (Drosophila) homolog 4 antikoerper, sprouty homolog 4 (Drosophila) antikoerper, Spry4 antikoerper, SPRY4 antikoerper, spry4 antikoerper

Hintergrund: SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS, MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).
Alias Symbols: -
Protein Interaction Partner: GRB2, SPRY2, SPRY4, TESK1, RAF1, CBL,
Protein Size: 322

Molekulargewicht: 35 kDa

Gen-ID: 81848

NCBI Accession: NM_030964, NP_112226

UniProt: Q9C004