FANCE Antikörper (AA 1-13)

Produktnummer ABIN129609

Hersteller Produkt- Nr.: 600-401-673

Produktdetails anti-FANCE Antikörper

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Bindungsspezifität: AA 1-13

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Hersteller Produkt- Nr.: 600-401-673

Hersteller: Rockland

Verwendungszweck: FANCE Antibody

Produktmerkmale: Synonyms: rabbit anti-FANCE antibody, FANC-E, FANC E, FACE antibody, FAE antibody, Fanconi anemia group E protein, Fanconi anemia complementation group E antibody

Aufreinigung: This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

Sterilität: Sterile filtered

Immunogen:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1-13 of Human FANCE. This Fanconi anemia protein promotes the nuclear accumulation of FANCC.  FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage.  LocusLink ID 2178, SwissProt accession number Q9HB96

Immunogen Type: Conjugated Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide.  Reactivity in other immunoassays is unknown.

Western Blot Dilution: 1:500- 1:2,000

ELISA Dilution: 1:10,000 - 1:50,000

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu FANCE

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Andere Bezeichnung: FANCE (FANCE Produkte)

Hintergrund: Background: Fanconi anemia group E protein (FANCE) is part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. It is required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2.

Gen-ID: 2178

NCBI Accession: NP_068741

UniProt: Q9HB96

Pathways: DNA Reparatur