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FANCA Antikörper (AA 995-1009)

Dieses Anti-FANCA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FANCA in WB und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Rockland
Produktnummer ABIN129606
Hersteller Produkt- Nr.: 600-401-670

Kurzübersicht für FANCA Antikörper (AA 995-1009) (ABIN129606)

Target

Alle FANCA Antikörper anzeigen
FANCA (Fanconi Anemia Group A Protein (FANCA))

Reaktivität

  • 48
  • 19
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 61
  • 3
Kaninchen

Klonalität

  • 61
  • 3
Polyklonal

Konjugat

  • 34
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FANCA Antikörper ist unkonjugiert

Applikation

  • 33
  • 25
  • 13
  • 13
  • 12
  • 10
  • 8
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 12
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 995-1009

    Hersteller Produkt- Nr.

    600-401-670

    Hersteller

    Rockland

    Verwendungszweck

    FANCA Antibody

    Kreuzreaktivität (Details)

    This affinity-purified antibody is directed against human FANCA protein.

    Produktmerkmale

    Synonyms: rabbit anti-FANCA antibody, FANC-A, FANC A, Fanconi anemia group A protein, FAA antibody, FACA antibody, FAH antibody, FANCH antibody

    Aufreinigung

    The product was affinity purified from monospecific antiserum by immunoaffinity purification.

    Sterilität

    Sterile filtered

    Immunogen

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 995-1009 of human FANCA protein.

    Immunogen Type: Conjugated Peptide

    Isotyp

    IgG
  • Applikationshinweise

    Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a main band at approximately 163 kDa in size corresponding to FANCA by western blotting in the appropriate cell lysate or extract or human tissue.

    Western Blot Dilution: 1:500 - 1:3,000

    ELISA Dilution: 1:15,000 - 1:60,000

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    2.2 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Smogorzewska, Matsuoka, Vinciguerra, McDonald, Hurov, Luo, Ballif, Gygi, Hofmann, DAndrea, Elledge: "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).

  • Target

    FANCA (Fanconi Anemia Group A Protein (FANCA))

    Andere Bezeichnung

    FANCA

    Hintergrund

    Background: FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Diseases associated with FANCA include Fanconi anemia complementation group a and Congenital Hypoplastic Anemia.

    Gen-ID

    2175, 66880553

    UniProt

    O15360

    Pathways

    DNA Reparatur
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