Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

RAD23B Antikörper (AA 155-180)

Dieses Anti-RAD23B-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von RAD23B in WB und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Rockland
Produktnummer ABIN129561
Hersteller Produkt- Nr.: 600-101-391

Kurzübersicht für RAD23B Antikörper (AA 155-180) (ABIN129561)

Target

Alle RAD23B Antikörper anzeigen
RAD23B (RAD23 Homolog B (RAD23B))

Reaktivität

  • 89
  • 38
  • 36
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Human

Wirt

  • 67
  • 22
Ziege

Klonalität

  • 67
  • 22
Polyklonal

Konjugat

  • 54
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RAD23B Antikörper ist unkonjugiert

Applikation

  • 68
  • 30
  • 25
  • 17
  • 15
  • 14
  • 13
  • 13
  • 10
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 155-180

    Hersteller Produkt- Nr.

    600-101-391

    Hersteller

    Rockland

    Verwendungszweck

    HR23B Antibody

    Kreuzreaktivität (Details)

    Reactivity occurs against human HR23B protein.

    Produktmerkmale

    Synonyms: goat anti-HR23B antibody, hHR23B antibody, mHR23B antibody, p58 antibody, RAD23 (S. cerevisiae) homolog B antibody, UV excision repair protein RAD23 homolog B, XP-C repair-complementing complex 58 kDa protein

    Aufreinigung

    This is an affinity-purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

    Sterilität

    Sterile filtered

    Immunogen

    Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 155-180 of human HR23B protein.

    Immunogen Type: Conjugated Peptide

    Isotyp

    IgG
  • Applikationshinweise

    Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 58 kDa in size corresponding to HR23B by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:500 - 1:2,000

    ELISA Dilution: 1:2,000 - 1:10,000

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.1 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Crosby, Kulshreshtha, Ivan, Glazer: "MicroRNA regulation of DNA repair gene expression in hypoxic stress." in: Cancer research, Vol. 69, Issue 3, pp. 1221-9, (2009) (PubMed).

    Shen, Valencia, Szostak, Szostak, Dong, Liu: "Scanning the human proteome for calmodulin-binding proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 17, pp. 5969-74, (2005) (PubMed).

  • Target

    RAD23B (RAD23 Homolog B (RAD23B))

    Andere Bezeichnung

    RAD23B

    Hintergrund

    Background: HR23B (also known as UV excision repair protein RAD23 homolog B, XP-C repair complementing complex 58 kDa protein and p58) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

    Gen-ID

    5887, 4506387

    UniProt

    P54727

    Pathways

    DNA Reparatur
Sie sind hier:
Chat with us!