Cathepsin L Antikörper

Produktnummer ABIN127049

Produktdetails anti-Cathepsin L Antikörper

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Detects both the proenzyme and the mature form of cathepsin L.

Aufreinigung: Affinity purified

Immunogen: Synthetic peptide surrounding amino acid 223 of human Cathepsin L

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to -70 °C.

Details zu Cathepsin L

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Andere Bezeichnung: Cathepsin L1 (CTSL1 Produkte)

Synonyme: CATL antikoerper, CTSL1 antikoerper, MEP antikoerper, 1190035F06Rik antikoerper, Ctsl1 antikoerper, fs antikoerper, nkt antikoerper, CATHL antikoerper, CatL antikoerper, Ctsl antikoerper, CTSL antikoerper, mep antikoerper, catl antikoerper, ctsl antikoerper, cpl-1 antikoerper, MGC80629 antikoerper, MGC107932 antikoerper, LOC663234 antikoerper, 26-29-p antikoerper, Cp1 antikoerper, si:dkey-121a11.6 antikoerper, CTSV antikoerper, catL antikoerper, cb15 antikoerper, ctsl1b antikoerper, hgg1 antikoerper, wu:fb30g09 antikoerper, zgc:92089 antikoerper, cathepsin L antikoerper, cathepsin V antikoerper, cathepsin L L homeolog antikoerper, cathepsin L1 antikoerper, Cathepsin L1 antikoerper, Cathepsin L antikoerper, testin gene antikoerper, cathepsin 12 antikoerper, cathepsin Lb antikoerper, cathepsin L.1 antikoerper, CTSL antikoerper, Ctsl antikoerper, CTSV antikoerper, ctsl.L antikoerper, ctsl antikoerper, LOC100008830 antikoerper, catl1 antikoerper, 26-29-p antikoerper, catl antikoerper, Tsp_11596 antikoerper, Testin antikoerper, cts12 antikoerper, LOC102156614 antikoerper, ctslb antikoerper, ctsl.1 antikoerper

Hintergrund: Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be processed by cleavage of the 96 amino acid propeptide, to generate the active two-chain form made up of 21 and 5 kDa subunits. Mature Cathepsin L is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. The fact that Cathepsin L is also capable of degrading extracellular matrix proteins suggests that it may play a role in invation and metastasis and could be a useful prognostic indicator for cancer.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein

Gen-ID: 1514

NCBI Accession: NP_001903

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades