CASP5 Antikörper
Kurzübersicht für CASP5 Antikörper (ABIN126975)
Target
Alle CASP5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- The affinity purified antibody preferentially detects the intermediate (32 kDa) and the fully (20 kDa) cleaved caspase-5.
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Aufreinigung
- Immunoaffinity purified
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Immunogen
- Synthetic peptide surrounding amino acids 162 of human caspase-5
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Applikationshinweise
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Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.2 mg/mL
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Buffer
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA and 0.01 % thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C/-80 °C
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Informationen zur Lagerung
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
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Andere Bezeichnung
- Caspase-5
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Hintergrund
- Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-5 is also known as Ich-3 and ICErel-III and can proteolytically processed by granzyme B. Over expression of caspase-5 induces apoptosis in Rat-1 and HeLa cells, which can be inhibited by CrmA and Bcl-2.Synonyms: CASP-5, CASP5, ICE(rel)-III, ICH-3 protease, ICH3, TY protease
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Gen-ID
- 838
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NCBI Accession
- NP_001129581
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UniProt
- P51878
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Pathways
- Inflammasome
Target
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