Cytochrome C Antikörper

Produktnummer ABIN126969

Der Kaninchen Polyklonal anti-Cytochrome C Antikörper (ABIN126969) detektiert spezifisch Cytochrome C in WB und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Cytochrome C Antikörper (ABIN126969)

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytochrome C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-Cytochrome C Antikörper

Sequenz: surroundin g amino acid 70

Spezifität: The cytochrome c antibody detects the 12.6 kDa cytochrome c.

Aufreinigung: Protein A purified

Immunogen: Synthetic peptide corresponding to residues surrounding amino acid 70 of rat cytochrome c.

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL, Jurkat cell lysate, NIH3T3 cell lysate, and rat kidney tissue lysatecan be used as positive controls. Immunoprecipitation: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu Cytochrome C

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Andere Bezeichnung: Cytochrome C

Hintergrund: Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases.Synonyms: CYC, CYCS

Gen-ID: 54205

NCBI Accession: NP_061820

UniProt: P99999

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity