Lipoprotein Lipase Antikörper

Produktnummer ABIN125994

Dieses Anti-Lipoprotein Lipase-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Lipoprotein Lipase in WB, IHC (fro), Func und EIA. Geeignet für Human und Rind (Kuh).

Kurzübersicht für Lipoprotein Lipase Antikörper (ABIN125994)

Target: Lipoprotein Lipase (LPL)

Reaktivität: Human, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Lipoprotein Lipase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)

Klon: Mab-7

Produktdetails anti-Lipoprotein Lipase Antikörper

Spezifität: This Monoclonal antibody is directed against the CII binding site. Blocks the catalytic activity of Bovine milk lipase. A small partial cross-reactivity with Human Heparin Plasma Lipase activity was observed (Ref. 1).

Kreuzreaktivität (Details): Species reactivity (tested):Bovine, weak cross-reactivity with Human.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Purified Bovine Lipoprotein Lipase

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Immunoblotting. Immunohistochemistry (1/10). Dilution buffer: PBS with 0.5 % BSA and 0.1 % Na-Azide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1 mL distilled water

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Lipoprotein Lipase

Target: Lipoprotein Lipase (LPL)

Andere Bezeichnung: Lipoprotein Lipase

Hintergrund: Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.Synonyms: EC=3.1.1.34, LIPD, LPL

Gen-ID: 4023

NCBI Accession: NP_000228

UniProt: P06858

Pathways: Lipid Metabolism