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HLA-DR Antikörper (PE)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch HLA-DR in FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.
Produktnummer ABIN125743

Kurzübersicht für HLA-DR Antikörper (PE) (ABIN125743)

Target

HLA-DR

Reaktivität

  • 146
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Human

Wirt

  • 124
  • 15
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  • 1
Maus

Klonalität

  • 143
  • 6
  • 1
Monoklonal

Konjugat

  • 53
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  • 10
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  • 4
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  • 3
  • 3
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  • 2
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  • 2
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  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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Dieser HLA-DR Antikörper ist konjugiert mit PE

Applikation

  • 128
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  • 2
  • 1
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Flow Cytometry (FACS)

Klon

MEM-12
  • Verwendungszweck

    Anti-HLA-DR PE

    Spezifität

    The antibody MEM-12 recognizes a common extracellular epitope on human HLA-DR which is dependent on the association of alpha and beta chains. DR is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).

    Kreuzreaktivität (Details)

    Human

    Aufreinigung

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    thymocyte membrane

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Rekonstitution

    No reconstitution is necessary.

    Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.
    Avoid prolonged exposure to light.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." in: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).

  • Target

    HLA-DR

    Andere Bezeichnung

    HLA-DR

    Hintergrund

    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.

    Pathways

    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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