Leukotriene B4 Receptor/BLT Antikörper

Produktnummer ABIN122284

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Leukotriene B4 Receptor/BLT in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Leukotriene B4 Receptor/BLT Antikörper (ABIN122284)

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Leukotriene B4 Receptor/BLT Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Leukotriene B4 Receptor/BLT Antikörper

Spezifität: Reacts with Leukotriene B4 Receptor BLTR1/P2Y7 (Family: GPCR, Subfamily: Chemoattractant). BLAST analysis of the peptide immunogen showed no homology with other Human proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Peptide Immunoaffinity Chromatography

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin embedded sections: 5-10 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Leukotriene B4 Receptor/BLT

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Andere Bezeichnung: LTB4R / BLTR

Hintergrund: BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes. Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor. Part of the coding regions of BLTR2 (LS57180) have been duplicated and are part of the 5' UTR noncoding regions of the clusters BLT1 (LS190955) and CIDE-B (LS54843) on chromosome 14. BLTR1 has been reported in blood, bone marrow, brain, heart, liver, and skeletal muscle. In addition, BLTR1 has been shown to be highly expressed in leukocytes and lymphoid tissues such as spleen, thymus, and lymph node. ESTs have been isolated from B-cell/lung/testis, breast, colon, eye, kidney, skin, spleen, testis, and tonsil libraries.Synonyms: BLT, BLT1, CMKRL1, Chemoattractant receptor-like 1, G-protein coupled receptor 16, GPR16, LTB4-R 1, Leukotriene B4 receptor 1, P2RY7, P2Y purinoceptor 7, P2Y7

Gen-ID: 1241

UniProt: Q15722