HTR1F Antikörper (C-Term)

Produktnummer ABIN121983

Der Kaninchen Polyklonal anti-HTR1F Antikörper (ABIN121983) detektiert spezifisch HTR1F in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für HTR1F Antikörper (C-Term) (ABIN121983)

Target: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTR1F Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HTR1F Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects human Serotonin receptor 1F (HTR1F) at C-term. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HTR1E (71 %), HTR1D (59 %), HTR1B (59 %).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat (see 'Immunogen Remarks')Species reactivity (tested):Human

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemstry on paraffin embedded sections: 2-3 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu HTR1F

Target: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Andere Bezeichnung: Serotonin Receptor 1F (HTR1F)

Hintergrund: 5-HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5-HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.Synonyms: 5-HT-1F, 5-hydroxytryptamine receptor 1F, HTR1EL

Gen-ID: 3355

UniProt: P30939

Pathways: JAK-STAT Signalweg