HTR1F Antikörper

Produktnummer ABIN121982

Der Kaninchen Polyklonal anti-HTR1F Antikörper wird verwendet zum Nachweis von HTR1F in Proben von Human, Ratte und Maus. Er wurde validiert für IHC (p).

Kurzübersicht für HTR1F Antikörper (ABIN121982)

Target: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTR1F Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HTR1F Antikörper

Spezifität: This antibody reacts to Serotonin Receptor 1F (Family: GPCR, Subfamily: Serotonin).

Aufreinigung: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemsiry on paraffin embedded sections: 5-8 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu HTR1F

Target: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Andere Bezeichnung: Serotonin Receptor 1F (HTR1F)

Hintergrund: 5-HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5-HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.Synonyms: 5-HT-1F, 5-hydroxytryptamine receptor 1F, HTR1EL

Gen-ID: 3355

UniProt: P30939

Pathways: JAK-STAT Signalweg