CCR1 Antikörper (Extracellular Domain)

Produktnummer ABIN121947

Der Kaninchen Polyklonal anti-CCR1 Antikörper (ABIN121947) detektiert spezifisch CCR1 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für CCR1 Antikörper (Extracellular Domain) (ABIN121947)

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CCR1 Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: Reacts with human C-C Chemokine Receptor 1 (CCR1, Family: GPCR, subfamily: Chemokine).

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic petide - KLH conjugated.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin embedded sections: 5 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CCR1

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Andere Bezeichnung: CD191 / CCR1

Hintergrund: CCR1, a Chemokine Receptor, affects stem cell proliferation and mediates systemic inflammatory responses. This receptor is stimulated by the beta chemokines RANTES, MCP-1, and MIP-1 alpha. Disruption of CCR1 enhances protection from pulmonary inflammation and reduces the development of respiratory distress syndrome in rat. CCR1 is widely expressed, particularly in hematopoietic cells from blood, vessels, and bone marrow. This receptor has also been reported to be expressed in lung, brain, placenta, heart, skeletal muscle, and kidney. ESTs have been isolated from blood, kidney, liver/spleen, lung, placenta, uterus, and vessel libraries.Synonyms: C-C CKR-1, C-C chemokine receptor type 1, CC-CKR-1, CCR-1, CMKBR1, CMKR1, HM145, LD78 receptor, MIP1 alpha Receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, SCYAR1

Gen-ID: 1230

UniProt: P32246