Collagen Type I Antikörper

Produktnummer ABIN121921

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch Collagen Type I in IHC (fro) und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Collagen Type I Antikörper (ABIN121921)

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Collagen Type I Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Produktdetails anti-Collagen Type I Antikörper

Spezifität: This antibody recognises human Type 1 collagen. It has been cross-adsorbed against collagen types II, III, IV, V and VI. Results from ELISA demonstrate < 10 % cross-reactivity with other collagen types.

Produktmerkmale: Synonyms: COL1A1, COL1A2, Alpha-1 type I collagen, Alpha-2 type I collagen

Aufreinigung: Affinity chromatography

Immunogen: Human type 1 collagen

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on frozen sections (1: 10 - 1: 20). ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.4 mg/mL

Buffer: 100 mM Borate buffered saline, pH 8.0, without preservatives and stabilizers.

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots, undiluted) at -20 °C. Avoid repeated freezing and thawing. Should thisproduct contain a precipitate we recommend microcentrifugation before use.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Collagen Type I

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Andere Bezeichnung: Collagen Type I

Hintergrund: Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.Synonyms: Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2

Gen-ID: 1277

UniProt: P02452