Interferon gamma Antikörper
Kurzübersicht für Interferon gamma Antikörper (ABIN121883)
Target
Alle Interferon gamma (IFNG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity Chromatography on protein G
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Immunogen
- Recombinant chicken Interferon Gamma
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Isotyp
- IgG
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Applikationshinweise
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ELISA. Western Blot: This antibody detects a band of approximately 18 kDa. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS without stabilizer or preservative
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Konservierungsmittel
- Without preservative
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Lagerung
- -20 °C
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Informationen zur Lagerung
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Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
Haltbarkeit
- 12 months
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- Interferon gamma (IFNG)
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Andere Bezeichnung
- IFNG / Interferon gamma
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Hintergrund
- Original studies investigating the properties of chicken Interferon (chIFN), revealed properties similar to mammalian IFN type I (IFNI), and it has since become apparent that there are at least three distinct chicken interferon proteins, designated as chIFN-alpha, chIFN-beta and chIFN-gamma. chIFN-gamma was first identified, when supernatant from chicken spleen cells stimulated with concanavalin A (ConA ), displayed macrophage-activating factor (MAF) activity - the principle function of mammalian type II IFNgamma. Several independent studies have since supported the existence of this chicken homolog, by the cloning of IFN-gamma cDNA from activated chicken T cells and demonstrating that recombinant chicken IFNgamma strongly upregulates the expression of MHC class II and iNOS genes.Synonyms: IFN-gamma, gamma IFN
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UniProt
- P49708
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Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie
Target
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