Endonuclease G Antikörper (AA 55-70)

Produktnummer ABIN121687

Produktdetails anti-Endonuclease G Antikörper

Target: Endonuclease G (ENDOG)

Bindungsspezifität: AA 55-70

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endonuclease G Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding to amino acids 55 - 70 of endonuclease G. AA Sequence: GGPRGPGELAKYGLP

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 μg/mL - 2 μg/mL, this antibody detects a band of approximately 35 kDa in HepG2 and 3T3 cell lysates. Immunohistochemistry on paraffin sections: 15 μg/mL, Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Human pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu Endonuclease G

Target: Endonuclease G (ENDOG)

Andere Bezeichnung: Endonuclease G (ENDOG Produkte)

Hintergrund: Endonuclease G is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. endoG is reported to act independently of caspases and may represent a caspase independent apoptotic pathway initiated from the mitochondria.Synonyms: ENDOG

UniProt: Q14249

Pathways: Apoptose