GAD Antikörper (C-Term)

Produktnummer ABIN121539

Dieses Anti-GAD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GAD in WB, IHC (p), IHC (fro) und EIA. Geeignet für Human, Maus, Ratte und Cat.

Kurzübersicht für GAD Antikörper (C-Term) (ABIN121539)

Target: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Reaktivität: Human, Maus, Ratte, Cat

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Produktdetails anti-GAD Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Also reacts to: GAD2 / GAD65

Produktmerkmale: Synonyms: Glutamate decarboxylase 1, GAD-67, Glutamate decarboxylase 67 kDa isoform, 67 kDaglutamic acid decarboxylase

Aufreinigung: Ammonium Sulphate Precipitation.

Immunogen: Synthetic peptide sequence from the C-terminus of GADAA Sequence: D-F-L-I-E-E-I-E-R-L-G-Q-D-L

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1/1000-1/10000. Immunohistochemistry on Frozen Sections: 1/200-1/5000. Recommended Positive Control: Brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GAD

Target: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Andere Bezeichnung: GAD1 / GAD67

Hintergrund: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.Synonyms: 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 1, Glutamate decarboxylase 67 kDa isoform

Gen-ID: 2571

UniProt: Q99259