PPM1A Antikörper

Produktnummer ABIN121149

Dieses Anti-PPM1A-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PPM1A in WB, IP, IHC (p) und EIA. Geeignet für Human und Maus.

Kurzübersicht für PPM1A Antikörper (ABIN121149)

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPM1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: P6c7

Produktdetails anti-PPM1A Antikörper

Spezifität: This antibody detects Protein Phosphatase 2C alpha (PP2C alpha).

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human PP2C alpha protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: Recommended dilution range: 1:250 approx. 1:1000. Recommended starting dilution: 1:250. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C for one month or at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu PPM1A

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Andere Bezeichnung: Protein Phosphatase 1A / PPM1A

Hintergrund: Protein phosphatase 2C(PP2Cα) is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.Synonyms: PP2C-alpha, PPPM1A, Protein phosphatase 2C isoform alpha, Protein phosphatase IA

UniProt: P35813