MHC Class I RT1.Aa alpha-Chain (RT1.AA) Antikörper

Produktnummer ABIN120718

Dieser Maus Monoklonal Antikörper detektiert spezifisch MHC Class I RT1.Aa alpha-Chain in FACS, IHC (fro) und IP. Es zeigt Reaktivität gegenüber Proben von Ratte.

Kurzübersicht für MHC Class I RT1.Aa alpha-Chain (RT1.AA) Antikörper (ABIN120718)

Target: MHC Class I RT1.Aa alpha-Chain (RT1.AA)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Klon: OX-18

Produktdetails

Aufreinigung: Protein G Chromotraphy

Immunogen: Rat spleen membrane glycoproteins depleted of Ia-A antigens. Donor: BALB/c spleen. Fusion Partner: X63 Ag8.653

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS

Konservierungsmittel: Azide free

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Handle under aseptic conditions.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Antigendetails

Target: MHC Class I RT1.Aa alpha-Chain (RT1.AA)

Andere Bezeichnung: MHC Class I (RT1Aa)

Hintergrund: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.Synonyms: RT1 class I histocompatibility antigen AA alpha chain