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CD59 Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD59 in FACS und Func. Er zeigt eine Reaktivität gegenüber Human und Schwein.

Produktnummer ABIN120694

Kurzübersicht für CD59 Antikörper (ABIN120694)

Target

Alle CD59 Antikörper anzeigen

CD59

Reaktivität

160
15
11
8
5
4
3
1
1

Human, Schwein

Wirt

Maus

Klonalität

Monoklonal

Konjugat

86
25
15
14
8
4
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1

Dieser CD59 Antikörper ist unkonjugiert

Applikation

106
82
67
46
38
30
27
23
16
14
13
13
11
11
9
8
3
3
3
1
1
1

Flow Cytometry (FACS), Functional Studies (Func)

Klon

MEM-129

Discover our top product CD59 Primärantikörper

Spezifität

The antibody MEM-129 reacts with CD59 (Protectin).

Aufreinigung

Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.

Reinheit

> 95 % (by SDS-PAGE).

Immunogen

Human peripheral blood lymphocytes

Isotyp

IgM
anti-CD59 (CD59) (AA 31-111) antibody
CD59 Reaktivität: Human FACS, IHC, ELISA, ICC Wirt: Maus Monoclonal 8D2B8 unconjugated

anti-CD59 (CD59) (AA 74-110) antibody
CD59 Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB56691 unconjugated

anti-CD59 (CD59) antibody
CD59 Reaktivität: Human, Maus WB, FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43-5 unconjugated

anti-CD59 (CD59) antibody
CD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 unconjugated

anti-CD59 (CD59) (AA 31-111) antibody
CD59 Reaktivität: Human WB, FACS, IHC, ELISA, IF/ICC Wirt: Maus Monoclonal unconjugated

anti-CD59 (CD59) (AA 23-105) antibody
CD59 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD59 (CD59) (AA 1-128) antibody
CD59 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3G6 unconjugated

anti-CD59 (CD59) (AA 26-102) antibody
CD59 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD59 (CD59) antibody (Biotin)
CD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 Biotin

anti-CD59 (CD59) antibody (FITC)
CD59 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-43 FITC

Applikationshinweise

Flow Cytometry. Functional Studies (The antibody activates T-cells).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4

Konservierungsmittel

Azide free

Lagerung

4 °C

Informationen zur Lagerung

Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: one year from despatch.

Haltbarkeit

12 months
Target

CD59

Andere Bezeichnung

CD59

Hintergrund

CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

Gen-ID

966

UniProt

P13987

Pathways

Komplementsystem

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