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CD59 Antikörper

CD59 Reaktivität: Human, Schwein FACS, Func Wirt: Maus Monoclonal MEM-129 unconjugated

Produktnummer ABIN120694

Datenblatt (PDF)

Target Alle CD59 Antikörper anzeigen

CD59
Reaktivität
145

14

9

8

5

3

2

1

1
Human, Schwein
Wirt
90

74

6

6
Maus
Passende Sekundärantikörper
Klonalität
99

74

1
Monoklonal
Konjugat
81

21

15

14

6

4

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser CD59 Antikörper ist unkonjugiert
Applikation
103

70

47

43

33

28

26

17

14

14

13

13

11

11

8

3

3

3

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Spezifität

The antibody MEM-129 reacts with CD59 (Protectin).

Aufreinigung

Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.

Reinheit

> 95 % (by SDS-PAGE).

Immunogen

Human peripheral blood lymphocytes

Klon

MEM-129

Isotyp

IgM

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anti-CD59 (CD59) antibody
CD59 Reaktivität: Human, Maus FACS, WB, IP, IHC (p) Wirt: Maus Monoclonal MEM-43-5 unconjugated

anti-CD59 (CD59) (AA 31-111) antibody
CD59 Reaktivität: Human FACS, WB, IHC, ELISA, IF/ICC Wirt: Maus Monoclonal unconjugated

anti-CD59 (CD59) (AA 23-105) antibody
CD59 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD59 (CD59) (AA 1-128) antibody
CD59 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3G6 unconjugated

anti-CD59 (CD59) (AA 26-102) antibody
CD59 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD59 (CD59) antibody (Biotin)
CD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 Biotin

anti-CD59 (CD59) antibody (FITC)
CD59 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-43 FITC

Applikationshinweise

Flow Cytometry. Functional Studies (The antibody activates T-cells).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4

Konservierungsmittel

Azide free

Lagerung

4 °C

Informationen zur Lagerung

Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: one year from despatch.

Haltbarkeit

12 months
Target

CD59

Andere Bezeichnung

CD59 (CD59 Produkte)

Hintergrund

CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

Gen-ID

966

UniProt

P13987

Pathways

Komplementsystem