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CD33 Antikörper

CD33 Reaktivität: Human FACS Wirt: Maus Monoclonal HIM3-4 unconjugated
Produktnummer ABIN120672
  • Target Alle CD33 Antikörper anzeigen
    CD33
    Reaktivität
    • 165
    • 35
    • 15
    • 13
    • 7
    • 6
    • 3
    • 1
    Human
    Wirt
    • 92
    • 79
    Maus
    Klonalität
    • 89
    • 81
    • 1
    Monoklonal
    Konjugat
    • 56
    • 16
    • 13
    • 12
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD33 Antikörper ist unkonjugiert
    Applikation
    • 107
    • 99
    • 40
    • 30
    • 26
    • 26
    • 22
    • 22
    • 16
    • 13
    • 9
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The antibody HIM3-4 reacts with CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells, it is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
    Aufreinigung
    Protein-G affinity chromatography
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    NFMY-9s human cell line
    Klon
    HIM3-4
    Isotyp
    IgG1
    Top Product
    Discover our top product CD33 Primärantikörper
  • Applikationshinweise
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, pH ~7.4, 15 mM Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    CD33
    Andere Bezeichnung
    CD33 / SIGLEC3 (CD33 Produkte)
    Synonyme
    SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, Siglec-3 antikoerper, gp67 antikoerper, CD33 molecule antikoerper, CD33 antigen antikoerper, CD33 antikoerper, Cd33 antikoerper
    Hintergrund
    CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.Synonyms: Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, gp67
    Gen-ID
    945
    UniProt
    P20138
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