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Endoglin Antikörper

ENG Reaktivität: Human WB, FACS, IP Wirt: Maus Monoclonal MEM-226 unconjugated

Produktnummer ABIN120662

Datenblatt (PDF)

Target Alle Endoglin (ENG) Antikörper anzeigen

Endoglin (ENG)
Reaktivität
185

69

55

17

10

6

5

3

3

3

1
Human
Wirt
116

94

21

1
Maus
Passende Sekundärantikörper
Klonalität
117

114

1
Monoklonal
Konjugat
97

28

24

23

13

7

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Dieser Endoglin Antikörper ist unkonjugiert
Applikation
146

140

61

52

36

25

25

20

18

15

14

7

6

5

4

3

2

2

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Aufreinigung

Protein-A affinity chromatography

Reinheit

> 95 % pure (by SDS-PAGE)

Immunogen

Recombinant Vaccinia Virus containing human CD105 cDNA

Klon

MEM-226

Isotyp

IgG2a

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anti-Endoglin (ENG) (AA 27-137) antibody
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anti-Endoglin (ENG) (AA 26-136) antibody
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anti-Endoglin (ENG) (AA 26-136) antibody
ENG Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Endoglin (ENG) antibody
ENG Reaktivität: Human FACS, IHC, ELISA, ICC Wirt: Maus Monoclonal 3A9 unconjugated

anti-Endoglin (ENG) (AA 27-226) antibody
ENG Reaktivität: Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Endoglin (ENG) antibody
ENG Reaktivität: Human, Ratte WB, FACS, IP, CyTOF Wirt: Maus Monoclonal MEM-226 unconjugated

anti-Endoglin (ENG) (AA 601-658) antibody
ENG Reaktivität: Human, Ratte ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Endoglin (ENG) antibody (APC)
ENG Reaktivität: Human, Ratte FACS Wirt: Maus Monoclonal MEM-226 APC

anti-Endoglin (ENG) (AA 370-430) antibody
ENG Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Fow Cytometry. Immunoprecipitation. Western blotting (non-reducing conditions only).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit

12 months
Target

Endoglin (ENG)

Andere Bezeichnung

CD105 / Endoglin (ENG Produkte)

Hintergrund

CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbR-2 as a receptor for TGFb-1 and TGFb-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFb-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.Synonyms: END, ENG, HHT1, ORW, ORW1

UniProt

P17813