SIT1 Antikörper (PE)

Produktnummer ABIN120659

Produktdetails anti-SIT1 Antikörper (PE)

Target: SIT1 (Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIT1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: The antibody reacts with SHP2-interacting transmembrane adaptor protein (SIT) expressed exclusively in lymphoid organs.

Produktmerkmale: Synonyms: Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembraneadapter protein, Suppression-inducing transmembrane adapter 1

Immunogen: Bacterially produced recombinant intracellular fragment of human SIT

Klon: SIT-01

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for Flow cytometry (1/50, intracellular staining). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu SIT1

Target: SIT1 (Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))

Andere Bezeichnung: SIT1 / SIT (SIT1 Produkte)

Synonyme: SIT1 antikoerper, RP11-331F9.5 antikoerper, SIT antikoerper, SIT-R antikoerper, Sit antikoerper, signaling threshold regulating transmembrane adaptor 1 antikoerper, suppression inducing transmembrane adaptor 1 antikoerper, SIT1 antikoerper, Sit1 antikoerper

Hintergrund: SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development. Binding to Grb2 plays a pivotal role in signal transduction. Hubener et al. (2001) determined that the SIT gene contains 5 exons and spans 1.8 kb of genomic DNA. The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors.Synonyms: SHP2-interacting transmembrane adapter protein, Signaling threshold-regulating transmembrane adapter 1, Suppression-inducing transmembrane adapter 1

Gen-ID: 27240

UniProt: Q9Y3P8