CD47 Antikörper
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- Target Alle CD47 Antikörper anzeigen
- CD47
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD47 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- The antibody reacts with CD47 (Integrin Associated Protein), a 50-55 kDa membrane adhesion molecule (Thrombospondin Receptor, immunoglobulin supergene family) expressed on leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines.
- Aufreinigung
- CHT-Chromatography and Precipitation Methods
- Immunogen
- COS-7 (African green monkey) cells
- Klon
- MEM-122
- Isotyp
- IgM
- Top Product
- Discover our top product CD47 Primärantikörper
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anti-CD47 (CD47) antibody
CD47 Reaktivität: Human, Maus FACS, IF, IHC, StM Wirt: Maus Monoclonal B6H12-2 unconjugated
anti-CD47 (CD47) (AA 18-135) antibodyCD47 Reaktivität: Human FACS, IF, IHC, ELISA, StM, Coat Wirt: Maus Monoclonal CD47-3019 unconjugated
anti-CD47 (CD47) (AA 20-140) antibodyCD47 Reaktivität: Human WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD47 (CD47) (AA 18-219) antibodyCD47 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD47 (CD47) antibody (FITC)CD47 Reaktivität: Human, Schwein, Non-Human Primate FACS Wirt: Maus Monoclonal MEM-122 FITC
anti-CD47 (CD47) (AA 241-323) antibodyCD47 Reaktivität: Maus, Ratte FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD47 (CD47) (AA 18-135) antibodyCD47 Reaktivität: Human FACS, WB, IF, IHC, ELISA, StM, Coat Wirt: Maus Monoclonal CD47-2937 unconjugated
anti-CD47 (CD47) antibodyCD47 Reaktivität: Human, Schwein, Non-Human Primate FACS, WB, IHC (fro) Wirt: Maus Monoclonal MEM-122 unconjugated
anti-CD47 (CD47) antibodyCD47 Reaktivität: Human WB, IF, IHC, ELISA Wirt: Kaninchen Monoclonal 4G11 unconjugated Recombinant Antibody
anti-CD47 (CD47) (AA 44-141) antibodyCD47 Reaktivität: Human IF, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Flow cytometry. Western blotting (non-reducing conditions). Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH ~7.4, 15 mM Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
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Store the antibody at 2 - 8 °C. Do not freeze.
Shelf Life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- CD47
- Andere Bezeichnung
- CD47 (CD47 Produkte)
- Hintergrund
- CD47 is an ubiquitously expressed cell surface transmembrane glycoprotein interacting with several integrins and regulating their functions. Engagement of CD47 by soluble ligands or counter receptors modulates various signaling pathways, such as activation of heterotrimeric G proteins. Binding secreted thrombospondin-1, CD47 counteracts graft vascularization. CD47 acts also as a ligand for CD172a (signal regulatory protein a, SIRPa), an immune inhibitory receptor on macrophages, this interaction prevents phagocytosis of CD47-positive cells. Moreover, CD47-CD172a system affects cell migration, B cell adhesion and T cell activation. CD47 is also involved in modulation of chondrocyte responses to mechanical signals, and promotes neuronal development, being especially abundant in synapse-rich regions of brain and retina.Synonyms: Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, OA3
- Gen-ID
- 961
- UniProt
- Q08722
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