Der Maus Monoklonal anti-Transferrin Receptor Antikörper wird verwendet zum Nachweis von Transferrin Receptor in Proben von Ratte. Er wurde validiert für FACS.
CD71 is a homodimeric type II transmembrane protein, expressed by all proliferating cells and cells with a requirement for iron, including reticulocytes and capillary endothelium in brain. Transferrin receptor (CD71), transferrin and ferritin have been identified as specialised proteins which control the uptake, transport and storage of free iron in tissues, thereby maintaining iron homeostasis. An imbalance in iron homeostasis within the brain has been linked with the neurodegenerative diseases, Alzheimers, Parkinsons, Huntingtons and Multiple Sclerosis.Synonyms: TfR1, Transferrin receptor protein 1, p90