This antibody recognises the b chain of the rat CD8 cell surface antigen. This antibody is reported to block proliferative and cytotoxic responses of CD8 +ve effector cells in vitro.
Aufreinigung
Affinity chromatography on Protein G
Immunogen
Rat/mouse T cell hyrids expressing CD8. Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63 Ag.653 myeloma cell line.
Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore with 1 mL distilled water
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
RT/4 °C/-20 °C
Informationen zur Lagerung
Lyophilized: Store at 2-8 °C (preferably in a dessicator). Reconstituted: Aliquot and store at -20 °C.
Target
CD8B
(CD8b Molecule (CD8B))
Andere Bezeichnung
CD8 beta
Hintergrund
CD8 is expressed on thymocytes and peripheral cytotoxic/suppressor cells. CD8b is not expressed by NK cells or by intestinal intraepithelial T cells.Synonyms: CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain