CCL2 Antikörper

Produktnummer ABIN120345

Der Maus Monoklonal anti-CCL2 Antikörper (Klon 2-2-4A4-1A11) (ABIN120345) detektiert spezifisch CCL2 in IHC (p), EIA und ELISA (Detection). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CCL2 Antikörper (ABIN120345)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCL2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), ELISA (Detection)

Klon: 2-2-4A4-1A11

Produktdetails anti-CCL2 Antikörper

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Recombinant human MCP-1/MCAF (Macrophage Chemoattractant Activating Factor). Spleen cells from immunised BALB/c X ICR F1 mice were fused with cells of a mouse myeloma cell line.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/250 - 1/500 (as detection reagent).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.5 mL distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Details zu CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Andere Bezeichnung: MCP1 / CCL2

Hintergrund: This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2

Gen-ID: 9606

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylierungen bei SARS-CoV-2 Infektion