ITGB1 Antikörper
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- Target Alle ITGB1 Antikörper anzeigen
- ITGB1 (Integrin beta 1 (ITGB1))
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Reaktivität
- Maus, Ratte
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser ITGB1 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- Spezifität
- This antibody recognises the integrin beta 1 subunit (CD29). Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion.
- Aufreinigung
- Affinity Chromatography on Protein G.
- Endotoxin-Niveau
- Low Endotoxin
- Immunogen
- Purified mouse VLA-4 antigen. Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.
- Klon
- HM beta 1-1
- Isotyp
- IgG
- Top Product
- Discover our top product ITGB1 Primärantikörper
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- Applikationshinweise
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Flow Cytometry (1/50-1/100): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/mg. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS without preservatives.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- Target
- ITGB1 (Integrin beta 1 (ITGB1))
- Andere Bezeichnung
- CD29 / Integrin beta-1 (ITGB1 Produkte)
- Hintergrund
- CD29 is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12
- Gen-ID
- 16412
- NCBI Accession
- NP_034708
- UniProt
- P09055
- Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom
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