MHC Class I RT1.Aa alpha-Chain (RT1.AA) Antikörper

Produktnummer ABIN120149

Der Maus Monoklonal anti-MHC Class I RT1.Aa alpha-Chain Antikörper wird verwendet zum Nachweis von MHC Class I RT1.Aa alpha-Chain in Proben von Ratte. Er wurde validiert für FACS und IHC (fro).

Kurzübersicht für MHC Class I RT1.Aa alpha-Chain (RT1.AA) Antikörper (ABIN120149)

Target: MHC Class I RT1.Aa alpha-Chain (RT1.AA)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: F16-4-4

Produktdetails

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Partially purified rat MHC antigens. Spleen cells of immunised BALB/c mice were fused with cells from the NS-1 mouse myeloma line.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (1/100-1/200). Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Antigendetails

Target: MHC Class I RT1.Aa alpha-Chain (RT1.AA)

Andere Bezeichnung: MHC Class I (RT1Aa)

Hintergrund: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.Synonyms: RT1 class I histocompatibility antigen AA alpha chain

Gen-ID: 10116

UniProt: P16391