IL-2 Antikörper (FITC)

Produktnummer ABIN119946

Dieses Anti-IL-2-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von IL-2 in FACS. Geeignet für Human und Affe.

Kurzübersicht für IL-2 Antikörper (FITC) (ABIN119946)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reaktivität: Human, Affe

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-2 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: MQ1-17H12

Produktdetails anti-IL-2 Antikörper (FITC)

Aufreinigung: Affinity chromatography on Protein G

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry (neat - 1/10): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Membrane permeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung: Interleukin-2 / IL2

Hintergrund: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

Gen-ID: 9606

UniProt: P60568

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation