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beta-2 Microglobulin Antikörper

Der Maus Monoklonal Anti-beta-2 Microglobulin Antikörper wurde für FACS und IHC (fro) validiert. Er ist geeignet, beta-2 Microglobulin in Proben von Ratte zu detektieren.
Produktnummer ABIN119387

Kurzübersicht für beta-2 Microglobulin Antikörper (ABIN119387)

Target

Alle beta-2 Microglobulin (B2M) Antikörper anzeigen
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reaktivität

  • 254
  • 65
  • 49
  • 43
  • 11
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Ratte

Wirt

  • 159
  • 135
  • 9
  • 6
  • 2
  • 1
Maus

Klonalität

  • 179
  • 132
  • 1
Monoklonal

Konjugat

  • 140
  • 35
  • 25
  • 14
  • 14
  • 8
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser beta-2 Microglobulin Antikörper ist unkonjugiert

Applikation

  • 176
  • 142
  • 109
  • 97
  • 79
  • 54
  • 53
  • 39
  • 26
  • 21
  • 18
  • 17
  • 14
  • 13
  • 11
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon

TLD-3H12B
  • Spezifität

    This antibody recognises beta-2 Microglobulin, expressed at the surface of most cells in association with MHC Class I molecules.

    Aufreinigung

    Affinity Chromatography on Protein G.

    Immunogen

    Rat microglial cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse MOM myeloma cell line.

    Isotyp

    IgG1
  • Applikationshinweise

    Flow Cytometry: 1/10 - 1/20, use 10 μL of suggested working dilution to label 1x10^6 cells in 100 μL. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    Andere Bezeichnung

    beta-2-Microglobulin

    Hintergrund

    Beta 2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin

    Gen-ID

    24223

    NCBI Accession

    NP_036644

    UniProt

    P07151

    Pathways

    T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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