CD97 Antikörper

Produktnummer ABIN119250

Produktdetails anti-CD97 Antikörper

Target: CD97

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD97 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP)

Spezifität: The antibody recognizes an unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein-A affinity chromatography

Reinheit: > 95 % pure (by SDS-PAGE)

Immunogen: PHA-activated blood cells

Klon: MEM-180

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1/200 - 1/400, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD97

Target: CD97

Andere Bezeichnung: CD97 (CD97 Produkte)

Synonyme: AA409984 antikoerper, TM7LN1 antikoerper, adhesion G protein-coupled receptor E5 antikoerper, Adgre5 antikoerper, ADGRE5 antikoerper

Hintergrund: CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.Synonyms: Leukocyte antigen CD97

Gen-ID: 976

NCBI Accession: NP_001020331

UniProt: P48960