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CD97 Antikörper (FITC)

CD97 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-180 FITC
Produktnummer ABIN94253
  • Target Alle CD97 Antikörper anzeigen
    CD97
    Reaktivität
    • 66
    • 10
    • 4
    • 1
    • 1
    Human
    Wirt
    • 53
    • 19
    • 2
    • 2
    Maus
    Klonalität
    • 57
    • 19
    Monoklonal
    Konjugat
    • 46
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD97 Antikörper ist konjugiert mit FITC
    Applikation
    • 45
    • 33
    • 28
    • 26
    • 13
    • 13
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The antibody MEM-180 recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    PHA-activated peripheral blood cells
    Klon
    MEM-180
    Isotyp
    IgG1
    Top Product
    Discover our top product CD97 Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Wobus, Vogel, Schmücking, Hamann, Aust: "N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding." in: International journal of cancer. Journal international du cancer, Vol. 112, Issue 5, pp. 815-22, (2004) (PubMed).

  • Target
    CD97
    Andere Bezeichnung
    CD97 (CD97 Produkte)
    Synonyme
    AA409984 antikoerper, TM7LN1 antikoerper, adhesion G protein-coupled receptor E5 antikoerper, Adgre5 antikoerper, ADGRE5 antikoerper
    Hintergrund
    Adhesion G protein-coupled receptor E5,CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.,TM7LN1, ADGRE5
    Gen-ID
    976
    UniProt
    P48960
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