CD97 Antikörper
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- Target Alle CD97 Antikörper anzeigen
- CD97
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD97 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Spezifität
- The antibody recognizes an unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Protein-A affinity chromatography
- Reinheit
- > 95 % pure (by SDS-PAGE)
- Immunogen
- PHA-activated blood cells
- Klon
- MEM-180
- Isotyp
- IgG1
- Top Product
- Discover our top product CD97 Primärantikörper
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- Applikationshinweise
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Flow cytometry: 1/200 - 1/400, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CD97
- Andere Bezeichnung
- CD97 (CD97 Produkte)
- Hintergrund
- CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.Synonyms: Leukocyte antigen CD97
- Gen-ID
- 976
- NCBI Accession
- NP_001020331
- UniProt
- P48960
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