ERBB3 Antikörper

Produktnummer ABIN119014

Dieses Maus Monoklonal-Antikörper erkennt spezifisch ERBB3 in IP, FACS, IHC (fro) und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ERBB3 Antikörper (ABIN119014)

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ERBB3 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: SGP-1

Produktdetails anti-ERBB3 Antikörper

Spezifität: This antibody recognises an extra cellular domain of the ErbB3 protein.

Aufreinigung: Protein A chromatography

Immunogen: Wheat germ lectin purified ErbB3 protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry. Immunohistochemistry on frozen sections (5-10 μg/mL no special pretreatment required). Immunoprecipitation. ELISA. Not suitable for paraffin sections and western blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu ERBB3

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Andere Bezeichnung: ERBB3 / HER3

Hintergrund: ErbB3 is a 180 kD glycoprotein which is a growth factor receptor with tyrosine kinase activity. ErbB3 is expressed widely in normal human tissues, but is overexpressed in some tumours, including those of the breast, stomach, pancreas and colon.Synonyms: ERBB-3, HER-3, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, c-erbB-3

Gen-ID: 2065

NCBI Accession: NP_001005915

UniProt: P21860

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung