Hla Class I b7 Alpha,hla-B Antikörper (FITC)

Details zu Produkt Nr. ABIN118933, Anbieter: Anmelden zum Anzeigen
  • AS
  • HLAB
  • SPDA1
  • major histocompatibility complex, class I, B
  • HLA-B
Klonalität (Klon)
Monoklonal ()
Flow Cytometry (FACS)
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen Papain solubilized HLA-B7 antigen.
Klon BB7-1
Isotyp IgG1
Spezifität This antibody recognises the Human HLA-B7 antigen and does not cross-react with HLA-B27 or other related HLA antigens. It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (i.e. HLA-B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis.
Kreuzreaktivität (Details) Species reactivity (expected):Cynomolgus monkey.
Species reactivity (tested):Human.
Reinigung Affinity Chromatography on Protein G
Hintergrund HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. The HLA B gene is part of the human HLA complex on chromosome 6 and there are a large number of variant alleles of this gene.Synonyms: B-7 alpha chain, HLA class I histocompatibility antigen, HLAB, MHC class I antigen B7
Gen-ID 3106
NCBI Accession NP_005505
UniProt P01889
Applikationshinweise Flow cytometry: use 10 μL of neat - 1/10 diluted antibody to label 1x10^6 cells in 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.1 mg/mL
Buffer PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
 image for anti-Hla Class I b7 Alpha,hla-B antibody (FITC) (ABIN118933) ABIN118933 staining of HLA-B7 +ve human peripheral blood lymphocytes
Allgemeine Veröffentlichungen Yoshino, Ami, Terao, Tashiro, Honda: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, 2000 (PubMed).

Brodsky, Parham, Barnstable, Crumpton, Bodmer: "Monoclonal antibodies for analysis of the HLA system." in: Immunological reviews, Vol. 47, pp. 3-61, 1980 (PubMed).

Haben Sie etwas anderes gesucht?