FGF2 Antikörper

Produktnummer ABIN118917

Produktdetails anti-FGF2 Antikörper

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody recognises basic fibroblast growth factor (bFGF). The antibody binds strongly to bFGF attached to proteoglycans, but is competitively displaced by heparin. Not suitable for detecting bFGF bound to cell surface receptors.

Aufreinigung: Protein G chromatography

Immunogen: Recombinant human bFGF

Klon: MC-GF1

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on frozen sections. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FGF2

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Andere Bezeichnung: FGF Basic / FGF2 (FGF2 Produkte)

Synonyme: BFGF antikoerper, FGF-2 antikoerper, FGFB antikoerper, HBGF-2 antikoerper, Fgf-2 antikoerper, Fgfb antikoerper, bFGF antikoerper, fibroblast growth factor 2 antikoerper, fibroblast growth factor 2 (basic) antikoerper, FGF2 antikoerper, Fgf2 antikoerper, fgf2 antikoerper

Hintergrund: FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.Synonyms: BFGF, FGFB, Fibroblast growth factor 2 (basic), HBGF-2, HBGF2, Heparin-binding growth factor 2

Gen-ID: 2247

NCBI Accession: NP_001997

UniProt: P09038

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteine