Endoglin Antikörper (PE)
Kurzübersicht für Endoglin Antikörper (PE) (ABIN118833)
Target
Alle Endoglin (ENG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody recognises the human CD105 cell surface antigen, a glycoprotein homodimer of 95 kDa subunits.
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Aufreinigung
- Affinity Chromatography on Protein G.
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Immunogen
- Partially purified cell membrane antigens from fresh leukaemia cells
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Isotyp
- IgG1
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Applikationshinweise
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Flow cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore with 1.0 mL distilled water.
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Buffer
- PBS, pH 7.4, containing 0.09 % sodium azide as preservative and 1 % BSA as stabilizer.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- This product is photosensitive and should be protected from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
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- Endoglin (ENG)
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Andere Bezeichnung
- CD105 / Endoglin
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Hintergrund
- CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.Synonyms: END, ENG, HHT1, ORW, ORW1
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Gen-ID
- 9606
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UniProt
- P17813
Target
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