Endoglin Antikörper (FITC)

Produktnummer ABIN118831

Dieser Maus Monoklonal Antikörper erkennt spezifisch Endoglin in FACS. Er zeigt eine Reaktivität gegenüber Human und Pferd.

Kurzübersicht für Endoglin Antikörper (FITC) (ABIN118831)

Target: Endoglin (ENG)

Reaktivität: Human, Pferd

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Endoglin Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: SN6

Produktdetails anti-Endoglin Antikörper (FITC)

Spezifität: SM1177F recognizes the CD105 cell surface antigen.

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Partially purified cell membrane antigens from fresh leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/NS1/1-Ag4-1 myeloma cell line

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry (use 10 μL of neat antibody to label 10^6 cells in 100 μL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as a preservative and 1 % BSA as a stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: CD105 / Endoglin

Hintergrund: CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2. CD105 is a glycoprotein homodimer of 95 kD subunits. CD105 is expressed by endothelial cells, activated monocytes and some leukaemia cells.Synonyms: END, ENG, HHT1, ORW, ORW1

Gen-ID: 9606

UniProt: P17813