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CD59 Antikörper

CD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 unconjugated

Produktnummer ABIN118752

Datenblatt (PDF)

Target Alle CD59 Antikörper anzeigen

CD59
Reaktivität
145

14

9

8

5

3

2

1

1
Human
Wirt
90

74

6

6
Maus
Passende Sekundärantikörper
Klonalität
99

74

1
Monoklonal
Konjugat
81

21

15

14

6

4

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser CD59 Antikörper ist unkonjugiert
Applikation
103

70

47

43

33

28

26

17

14

14

13

13

11

11

8

3

3

3

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität

The antibody reacts with well defined epitope (W40, R-53) on CD59 (Protectin), an 18-20 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed on all hematopoietic cells, it is widely present on cells in all tissues.

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Aufreinigung

Affinity Chromatography on Protein A

Immunogen

Thymocytes and T lymphocytes

Klon

MEM-43

Isotyp

IgG2a

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anti-CD59 (CD59) antibody
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anti-CD59 (CD59) (AA 31-111) antibody
CD59 Reaktivität: Human FACS, WB, IHC, ELISA, IF/ICC Wirt: Maus Monoclonal unconjugated

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CD59 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

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CD59 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3G6 unconjugated

anti-CD59 (CD59) (AA 26-102) antibody
CD59 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD59 (CD59) antibody (Biotin)
CD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 Biotin

anti-CD59 (CD59) antibody (FITC)
CD59 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-43 FITC

Applikationshinweise

Immunoprecipitation. Flow Cytometry. Immunohistochemistry (paraffin sections) Recommended dilution: 10 m g/mL, Positive tissue: placenta
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Phosphate buffered saline (PBS) with 15 mM Sodium Azide as preservative, approx. pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

CD59

Andere Bezeichnung

CD59 (CD59 Produkte)

Hintergrund

CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

Gen-ID

966

NCBI Accession

NP_000602

UniProt

P13987

Pathways

Komplementsystem