ITGA2 Antikörper

Produktnummer ABIN118699

Produktdetails anti-ITGA2 Antikörper

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody recognises the integrin alpha2 subunit, which is a 160 kDa glycoprotein that non-covalently associates with the 130 kDa integrin beta1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, endothelial cells, monocytes and most adherent cell lines. Cross reacts with Cynomolgus monkey (3), Baboon and Rhesus monkey.

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line.

Klon: AK7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1/50 - 1/100, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on frozen sections: 1/500 - 1/1000. Recommended positive control tissue: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Andere Bezeichnung: CD49b / ITGA2 (ITGA2 Produkte)

Hintergrund: CD49b is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, approximately 50 % of monocytes and most adherent cell lines. MCA743 inhibits cell attachment to collagen.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2

Gen-ID: 3673

NCBI Accession: NP_002194

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex