RNF2 Antikörper (AA 189-201)

Produktnummer ABIN117940

Produktdetails anti-RNF2 Antikörper

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Bindungsspezifität: AA 189-201

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Huhn, Orang-Utan, Frosch, Schimpanse

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser RNF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: 1 msqavqtngt qplsktwels lyelqrtpqe aitdgleivv sprslhselm cpicldmlkn 61 tmttkeclhr fcadciital rsgnkecptc rkklvskrsl rpdpnfdali skiypsrdey 121 eahqervlar inkhnnqqal shsieeglki qamnrlqrgk kqqiengsga edngdsshcs 181 nasthsnqea gpsnkrtkts ddsgleldnn naamaidpvm dgaseielvf rphptlmekd 241 dsaqtryikt sgnatvdhls kylavrlale elrskgesnq mnldtasekq ytiyiatasg 301 qftvlngsfs lelvsekywk vnkpmelyya ptkehk

Spezifität: This antibody detects RING1B.

Kreuzreaktivität (Details): Species reactivity (expected):Zebrafish.
Species reactivity (tested):Human, Chimpanzee, Orangutan, Mouse, Rrat, Dog, Bovine, Frog and Chicken.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding aa 189-201 of Human RING1B protein

Anwendungsinformationen

Applikationshinweise: ELISA: 1/5,000-1/25,000. Western blot: 1/500-1/2,000. Expect a band approximately 38 kDa in size corresponding toRING1B by in the appropriate cell lysate or extract. Immunofluorescence.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.2 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 as buffer and 0.01 % (w/v) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C. DO NOT FREEZE!

Details zu RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Andere Bezeichnung: RNF2 (RNF2 Produkte)

Hintergrund: RING1B (also known as BAP1, DING, Polycomb-M33 interacting protein Ring1B, Ring finger protein 1b, Ring finger protein 2 and RNF2) is one of the PcG proteins. The polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), a ubiquitin-conjugating enzyme that possesses ubiquitin ligase activity.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B

Gen-ID: 6045

NCBI Accession: NP_009143

UniProt: Q99496