CD80 Antikörper
(3 Referenzen)-
- Target Alle CD80 Antikörper anzeigen
- CD80
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD80 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Marke
- BD Pharmingen™
- Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Klon
- L307-4
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD80 Primärantikörper
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anti-CD80 (CD80) (AA 35-288) antibody
CD80 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) antibodyCD80 Reaktivität: Maus, Hund FACS, IP, IHC (fro) Wirt: Armenischer Hamster Monoclonal 16-10A1 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibodyCD80 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-233 unconjugated
anti-CD80 (CD80) (AA 38-246) antibodyCD80 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 FITC
anti-CD80 (CD80) (AA 251-321) antibodyCD80 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PerCP
anti-CD80 (CD80) (Extracellular Domain) antibody (APC)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 APC
anti-CD80 (CD80) (Extracellular Domain) antibody (PE)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PE
anti-CD80 (CD80) antibodyCD80 Reaktivität: Human ELISA, IHC, ICC Wirt: Maus Monoclonal 2A2 unconjugated
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "Functional expression of B7/BB1 on activated T lymphocytes." in: The Journal of experimental medicine, Vol. 177, Issue 3, pp. 845-50, (1993) (PubMed).
: "Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy." in: Cell, Vol. 71, Issue 7, pp. 1065-8, (1993) (PubMed).
: "The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells." in: The Journal of experimental medicine, Vol. 173, Issue 3, pp. 759-62, (1991) (PubMed).
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: "Functional expression of B7/BB1 on activated T lymphocytes." in: The Journal of experimental medicine, Vol. 177, Issue 3, pp. 845-50, (1993) (PubMed).
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- Target
- CD80
- Andere Bezeichnung
- CD80 (CD80 Produkte)
- Hintergrund
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The L307.4 monoclonal antibody specifically reacts with B7/BB1, a 60 kDa transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80 is also expressed on activated CD4-positive and CD8-positive T cells, appearing late after activation suggesting that activated T cells may be capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell activation and a signal for IL-2 production.
Synonyms: B7.1, B7-1, Activation B7-1 antigen, B7, BB1, CD28LG, CD28LG1, LAB7 - Pathways
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