ITGB1 Antikörper
(1 reference)-
- Target Alle ITGB1 Antikörper anzeigen
- ITGB1 (Integrin beta 1 (ITGB1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ITGB1 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Marke
- BD Pharmingen™
- Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Klon
- HUTS-21
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product ITGB1 Primärantikörper
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anti-Integrin beta 1 (ITGB1) (AA 25-100) antibody
ITGB1 Reaktivität: Human, Maus, Ratte, Schaf, Kaninchen WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 Reaktivität: Human WB, FACS, ELISA, IHC Wirt: Maus Monoclonal 3B6 unconjugated
anti-Integrin beta 1 (ITGB1) (AA 140-383) antibodyITGB1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 Reaktivität: Human, Schwein, Hund WB, FACS, IP Wirt: Maus Monoclonal MEM-101A unconjugated
anti-Integrin beta 1 (ITGB1) antibody (PE)ITGB1 Reaktivität: Human, Schwein, Hund FACS Wirt: Maus Monoclonal MEM-101A PE
anti-Integrin beta 1 (ITGB1) (AA 297-380) antibodyITGB1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 Reaktivität: Human WB, FACS, ELISA, IHC, IF Wirt: Kaninchen Monoclonal 32A10 unconjugated Recombinant Antibody
anti-Integrin beta 1 (ITGB1) (AA 76-256) antibodyITGB1 Reaktivität: Human, Maus, Ratte, Hund, Huhn WB, IP, IF, IHC (f) Wirt: Maus Monoclonal 18-CD29 unconjugated
anti-Integrin beta 1 (ITGB1) (AA 454-714) antibodyITGB1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) (AA 140-383) antibodyITGB1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C2 unconjugated
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "Analysis of the activation state of alpha4beta1 integrin in human B cell lines derived from myeloma, leukemia or lymphoma." in: FEBS letters, Vol. 418, Issue 3, pp. 337-40, (1998) (PubMed).
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: "Analysis of the activation state of alpha4beta1 integrin in human B cell lines derived from myeloma, leukemia or lymphoma." in: FEBS letters, Vol. 418, Issue 3, pp. 337-40, (1998) (PubMed).
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- Target
- ITGB1 (Integrin beta 1 (ITGB1))
- Andere Bezeichnung
- CD29 (ITGB1 Produkte)
- Hintergrund
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Reacts with the 130 kDa integrin beta1 subunit, CD29, that is expressed following cell activation as a heterodimeric complex with one of nine distinct alpha subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. The HUTS-21 beta1 epitope is weakly expressed on resting lymphocytes, but is upregulated by TPA, Ca++ ionophore, or another CD29 antibody, TS2/16. This upregulation is Mn++ dependent and not supported by other divalent cations such as Ca++ and/or Mg++. The VLA receptors have a broad cellular distribution and interact with ligands like VCAm-1 and MAdCAM-1 during cell adhesion. They also interact with extra-cellular matrices including collagen, laminin, fibronectin and others. HUTS-21 antibody enhances adherence of TPA-activated lymphocytes to fibronectin.
Synonyms: Integrin beta1 Chain - Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom
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