Adiponectin Receptor 1 Antikörper (AA 2-36)

Produktnummer ABIN1169254

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Adiponectin Receptor 1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für Adiponectin Receptor 1 Antikörper (AA 2-36) (ABIN1169254)

Target: Adiponectin Receptor 1 (ADIPOR1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adiponectin Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Adiponectin Receptor 1 Antikörper

Bindungsspezifität: AA 2-36

Spezifität: Recognizes human adiponectin receptor 1.

Kreuzreaktivität: Human

Immunogen: Synthetic peptide corresponding to aa 2-36 (S2SHKGSVVAQGNGAPASNREADTVELAEL GPLLEE36) of human adiponectin receptor 1.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Neat serum containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Referenzen für anti-Adiponectin Receptor 1 Antikörper (ABIN1169254)

Corbetta, Redaelli, Pozzi, Bovo, Ratti, Redaelli, Pellegrini, Beck-Peccoz, Spada: "Fibrosis is associated with adiponectin resistance in chronic hepatitis C virus infection." in: European journal of clinical investigation, Vol. 41, Issue 8, pp. 898-905, (2011) (PubMed).

Details zu Adiponectin Receptor 1

Target: Adiponectin Receptor 1 (ADIPOR1)

Andere Bezeichnung: Adiponectin Receptor 1

Hintergrund: AdipoR1 is a receptor for globular and full-length adiponectin, an essential hormone secreted by adipocytes that acts as an antidiabetic. AdipoR1 is probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. It mediates increased AMPK, PPAR-alpha ligand activity, fatty acid oxidation and glucose uptake by adiponectin. It is a high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. It is widely expressed.

UniProt: Q96A54

Pathways: AMPK Signaling