IDO1 Antikörper
Kurzübersicht für IDO1 Antikörper (ABIN1169197)
Target
Alle IDO1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes human IDO. Detects a band of ~45 kDa by Western blot.
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Kreuzreaktivität
- Human
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Kreuzreaktivität (Details)
- Other species not tested.
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Sterilität
- 0.2 μm filtered
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Immunogen
- Recombinant human IDO.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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Konservierungsmittel
- Without preservative
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Haltbarkeit
- 12 months
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- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
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Andere Bezeichnung
- IDO
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Hintergrund
- IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
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UniProt
- P14902
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Pathways
- Activated T Cell Proliferation
Target
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