Dieses Anti-DLK1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von DLK1 in WB, ELISA, IHC und FACS. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Konservierungsmittel
Without preservative
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Haltbarkeit
12 months
Kluth, Radke, Kögler: "Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1." in: Stem cells international, Vol. 2013, pp. 985285, (2013) (PubMed).
Target
DLK1
(delta-Like 1 Homolog (Drosophila) (DLK1))
Andere Bezeichnung
DLK1
Hintergrund
The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.