DLK1 Antikörper (Extracellular Domain)

Produktnummer ABIN1169190

Zitiert in 1 Publikation. Der Ratte Monoklonal anti-DLK1 Antikörper (Klon PF105B) (ABIN1169190) detektiert spezifisch DLK1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für DLK1 Antikörper (Extracellular Domain) (ABIN1169190)

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser DLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: PF105B

Produktdetails anti-DLK1 Antikörper

Bindungsspezifität: Extracellular Domain

Verwendungszweck: anti-DLK1 (mouse), mAb (PF105B)

Spezifität: Recognizes mouse DLK1. Does not cross-react with human DLK1.

Keine Kreuzreaktivität: Human

Kreuzreaktivität (Details): Does not cross-react with human DLK1.

Produktmerkmale: Monoclonal Antibody. Recognizes mouse DLK1. Does not cross-react with human DLK1. Isotype: Rat IgG2akappa. Clone: PF105B. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant mouse DLK1 (extracellular domain).

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: approx. 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Referenzen für anti-DLK1 Antikörper (ABIN1169190)

Kim, Kang, Park, Kim, Park, Kim, Leem, Chu, Lee, Jho, Oh: "Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 6, pp. 1318-29, (2009) (PubMed).

Details zu DLK1

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Andere Bezeichnung: DLK1

Hintergrund:

Alternate Names/Synonyms: Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1

Product Description: The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

UniProt: Q09163